Current Projects

Translational Clinical projects

• Whole exome sequencing of patients with genetic conditions (developmental delay, Intellectual disability, unknown syndromes, etc) in collaboration with Genetic Health Service NZ – Northern Hub
• Exome sequencing of human leukaemia (e.g., donor cell leukaemias, unusual cases) in collaboration with ADHB

Research projects

• Transcriptome sequencing of murine and zebrafish leukaemia models
• Exome sequencing of murine and zebrafish leukaemia models
• Genome wide CRISPR knockout (GeCKO) screen sgRNA sequencing
• Whole exome sequencing for the CAVEAT clinical AML trial in collaboration with Monash University, Melbourne funded by NHMRC, Australia

Papers :

Kakadia PM, Van de Water N, Browett PJ, Bohlander SK. Efficient identification of somatic mutations in acute myeloid leukaemia using whole exome sequencing of fingernail derived DNA as germline control. Sci Rep. 2018;8:13751.

Leung EY, Askarian-Amiri ME, Singleton DC, Ferraro-Peyret C, Joseph WR, Finlay GJ, Broom RJ, Kakadia PM, Bohlander SK, Marshall E, Baguley BC. Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations. Front. Oncol., 12 October 2018 | https://doi.org/10.3389/fonc.2018.00425